Safety For Stress Urinary Incontinence

People who are going through stress urinary incontinence (SUI) may most likely suffer the adverse effects of a vaginal mesh. Actually, these women who have reportedly gone through vaginal bleeding, urinary problems, vaginal tightening, infections, mesh erosion, or pains during sex may have already filed a lawsuit against certain manufacturers and are hoping for a possible vaginal mesh settlement for the mesh injuries they sustained.

vaginal mesh lawsuitThis vaginal mesh update should be providing information for everyone to find safety practices when they happened to be affected by SUI. With this, they may want to get their interest up for duloxetine.

Duloxetine is a drug treatment for people suffering from depression and generalized anxiety disorder (GAD). Studies have been made about this drug and it was found out and published in the British Journal of Clinical Pharmacology that it can be used safely for the routine clinical care of women with SUI.

An observational study was conducted by medical researchers from the Johannes Gutenberg University in Mainz, Germany. It focuses on patients that newly started on a treatment for moderate-to-severe symptoms of stress urinary incontinence. The participants of this study were treated in a parallel 12-week (urologist and gynecologist patients) or 24-week (primary care physician) design and received duloxetine or other conservative treatment.

In the research, it was found out that duloxetine doses were lower than recommended. The qualitative spectrum of adverse events with duloxetine was similar to that seen in controlled studies, but the frequency was lower than in controlled studies (15.9 and 9.1 percent in the 12- and 24-week treatment groups, respectively). Medical care specialization, initial duloxetine dose (80 versus 20 mg/d), and taking in of any concurrent medication were factors considered to correlate with the study. Since the drug was used for depression and GAD, a positive screen for depressive disorder was very common in the 24-week study, but there were no attempts of suicide reported in either study.

The use of duloxetine is just one thing on the treatment of SUI, about which women should always be careful, considering that distressed recipients have been filing for a vaginal mesh lawsuit are increasing in number. We should also be attentive about new studies made in order to know about the next best things about this medical condition.


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The Benefits of Transvaginal Mesh

A transvaginal mesh support is more effective for repairing a common type of pelvic organ prolapse. Pelvic organ prolapse occurs when pelvic organs fall out of place, usually during child birth, a hysterectomy, or menopause. The transvaginal mesh is supposed to help promote the healing of the pelvic area better than simply stitching the connective tissue in the vaginal wall muscle back together. Transvaginal mesh may also be used to delay the need for a hysterectomy.

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Vaginal Mesh Use and Its Side Effects

Vaginal Mesh Complications and Side EffectsDuring the 1950s, vaginal mesh were used by physicians as a treatment for abdominal hernias. Twenty years passed and it was discovered that it can be used among women who have stress urinary incontinence (SUI) and pelvic organ prolapse (POP) by precision-cutting it into a particular shape. The two medical conditions with the help of the mesh was seen as an opportunity by many different manufacturers which is the reason why different designs and configurations were developed.

As different mesh implants were developed, different manufacturers have used different kinds of materials they think are suitable to make use of. Now, there are four categories for these mesh implants:

• non-absorbable synthetic (e.g., polypropylene or polyester)
• absorbable synthetic (e.g., poly(lactic-co-glycolic acid) or poly(caprolactone)
• biologic (e.g., acellular collagen derived from bovine or porcine sources)
• composite (i.e., a combination of any of the previous three categories)

Thousands of patients have been benefiting from this kind of effective treatment. Then, hundreds of women reported to have developed a range of serious health problems after using these vaginal meshes. Clearly, good things never last.

Last July 2011, the U.S. Food and Drug Administration (FDA) gave out a public warning among vaginal mesh users through issuing a report called “Update on Serious Complications Associated with Transvaginal Placement of Surgical Mesh.” The report contained the side effects linked to these conditions:

• Pelvic Organ Prolapse (POP). A condition in which a woman’s reproductive or pelvic organs fall into or through her vaginal opening.

• Stress Urinary Incontinence (SUI). A condition marked by the involuntary leakage of urine from a woman’s urethra during moments of physical stress.

Side Effects from the Use of Vaginal Mesh

It was found out from the FDA report available that erosion is the top complication resulting from the use of vaginal mesh. When the vaginal mesh wears out through the vaginal mucosa is when erosion can happen. Pains are then experienced by the woman and even her partner when they copulate because the rough and uncomfortable surface of the implant is then exposed. Multiple surgeries are then necessary to repair the erosion.

A significant number of patients have also reported about mesh contraction or the shrinking of the vaginal mesh. This condition can result to shortening, tightening and pain in the vagina.

There are also other side effects of vaginal mesh use such as:

• Bleeding
• Infection
• Pain
• Urinary problems
• Blood vessel, bladder, or bowel perforation
• Vaginal tightening
• Dyspareunia (pain during sex) caused by vaginal scarring and vaginal mesh erosion

Right now, local and national media are reporting many stories involving vaginal mesh and its side effects. Different manufacturers are facing compensatory claims by distressed implant recipients.


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